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- 在NCBI进行Blast P搜索结果显示猪CTSD氨基酸结构中含有Asn(Asparagine,天门冬酰胺)结构域,与天冬氨酸蛋白酶3D结构同源性高达99.7%,具有真核生物天冬氨酸蛋白酶的典型结构。The deduced 410 amino acid of CTSD was predicted to contain an Asn(Asparagine) domain which was the representative structure of lysosomal aspartic proteinase by blast in NCBI,and three-dimentional structure of porcine CTSD showed 99.7%25 alignment to that of mammalian CTSD.
- 在密码子应用上,第一位为A的氨基酸(赖氨酸lysine[AAA]、天冬酰胺asparagine[AAY]、丝氨酸serine[AGR])使用频率较高,这三种氨基酸占整个蛋白质氨基酸的30.59%(Lys9.95,Asn 9.52,Ser 11.12)。The most common amino acids and codons are lysine[AAA, asparagines[AAY] and serine[AGR]. The average content of AAA, AAY, AGR is 9.95%25, 9.52%25 and 11.12%25 respectively.