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- Objective To produce antisense vascular endothelial growth factor (VEGF) adenovirus expression vector for the antisense gene therapy of RA with antisense VEGF gene. 目的制备反义血管内皮生长因子(VEGF)腺病毒表达载体,为反义VEGF转基因治疗类风湿关节炎(RA)奠定基础。
- Keywords OPN;Viral Myocarditis;CoxsackievirusB3;Antisense gene therapy; 骨桥蛋白;病毒性心肌炎;柯萨奇B3病毒;反义基因治疗;
- The Study of Mechanisms and Antisense Gene Therapy of Immune Escape Through Fas/FasL Route in Neoplasms 肿瘤Fas/FasL途径免疫逃逸机制探讨及反义基因治疗对策的实验研究
- Keywords Monocyte chemotactic protein 1;Gene therapy;Antisense gene;Vein graft;Cationic lipids;Nanoparticle; 单核细胞趋化蛋白1;基因治疗;反义基因;静脉移植;阳离子脂质体;纳米粒子;
- antisense gene therapy 反义基因疗法
- The new methods also include antisense nucleic acid technique and ribozyme technique in gene therapy... 新发展的还有反义疗法以及应用核酶进行基因治疗等。
- Meanwhile, the application of antisense gene technology is prospected. 并对反义基因技术的应用进行了展望。
- Can the gene be fixed with gene therapy? 这种基因能用基因疗法治疗吗?
- Is Gene Therapy for Hypertension Possible? (基因治疗高血压可能吗?)
- The aim of gene therapy is to transfect DNA into target cells, in which ultilizing antisense oligonucleotides is a main method. 基因治疗是将DNA转染进入目的细胞,修复遗传错误或产生治疗因子。反义寡核苷酸的应用是基因治疗的主要手段之一。
- Finally I should say a word about germline gene therapy. 最后,我应当提一句生殖系基因疗法。
- We found that ATF-lys10 mediated uPAR antisense gene delivery could downregulate uPAR protein level as well as adhesion ability to fibronectin. 结果发现,ATF-lys10介导的uPAR反义核酸基因转移可以下调细胞uPAR蛋白水平,并降低细胞与纤连蛋白的粘附能力。
- Adenovirus mediated angiostatin gene therapy for rat glioma. 重组腺病毒载体介导血管抑素基因治疗大鼠脑胶质瘤的实验研究。
- Gene therapy is a new therapy technique for human being. 基因治疗是用于人类疾病治疗的一种新方法。
- Gene therapy is now impeded by lack of safe and effective vectors. 目前基因治疗受阻于缺乏安全有效的载体。
- Gene transfection is the key technique of gene therapy. 摘要基因治疗的关键技术是基因转移。
- Results of PCR amplification and restriction digestion showed that the fragment of antisense gene CYP86MF was introduced into pBI121 plasmid and the expression vector pBI35S-AMF was transferred into Agrobacterium successfully. PCR扩增和酶切鉴定结果表明;所构建的反义CYP86MF基因植物表达载体pBI35S-AMF是正确的;并已成功导入了根癌农杆菌中.
- The expression of K-RAS P21 protein in AsPC-1 and MiaPaCa-2 pancreatic carcinoma cells was obviously lower after the transduction of specific K-RAS Antisense gene,which has little impact on BxPC-3 pancreatic carcinoma cells. 转导K-RAS突变特异性反义基因后,AsPC-1和MiaPaCa-2胰腺癌细胞的K-RAS P21蛋白表达明显降低; BxPC-3胰腺癌细胞的K-RAS P21蛋白表达无明显变化。
- AIM:To study the effect of bcr - abl gene antisense phosphorothioate oligonucleotides(Aspo) on K562 cell line and explore its significance in chronic myelogencous leukemia (CML) gene therapy. 目的:研究 bcr-abl融合基因硫代磷酸反义寡核苷酸(Aspo)对 K562细胞生长特性的影响,探讨其在慢性粒细胞白血病(CML)基因治疗中的意义。
- Biotechnology derived pharmaceutical is a special class of drug manufactured by biotechnology. Its main varieties include recombinant cytokines and growth factors,monoclonal antibodies,vaccines,gene therapy and antisense olignucleotide. 生物技术药物是用现代生物技术生产的一类特定药物 ,主要种类包括基因重组的细胞因子或生长因子、单克隆抗体、疫苗、基因治疗制剂和反义核酸等。