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- Meanwhile, the application of antisense gene technology is prospected. 并对反义基因技术的应用进行了展望。
- We found that ATF-lys10 mediated uPAR antisense gene delivery could downregulate uPAR protein level as well as adhesion ability to fibronectin. 结果发现,ATF-lys10介导的uPAR反义核酸基因转移可以下调细胞uPAR蛋白水平,并降低细胞与纤连蛋白的粘附能力。
- Objective To produce antisense vascular endothelial growth factor (VEGF) adenovirus expression vector for the antisense gene therapy of RA with antisense VEGF gene. 目的制备反义血管内皮生长因子(VEGF)腺病毒表达载体,为反义VEGF转基因治疗类风湿关节炎(RA)奠定基础。
- Results of PCR amplification and restriction digestion showed that the fragment of antisense gene CYP86MF was introduced into pBI121 plasmid and the expression vector pBI35S-AMF was transferred into Agrobacterium successfully. PCR扩增和酶切鉴定结果表明;所构建的反义CYP86MF基因植物表达载体pBI35S-AMF是正确的;并已成功导入了根癌农杆菌中.
- The expression of K-RAS P21 protein in AsPC-1 and MiaPaCa-2 pancreatic carcinoma cells was obviously lower after the transduction of specific K-RAS Antisense gene,which has little impact on BxPC-3 pancreatic carcinoma cells. 转导K-RAS突变特异性反义基因后,AsPC-1和MiaPaCa-2胰腺癌细胞的K-RAS P21蛋白表达明显降低; BxPC-3胰腺癌细胞的K-RAS P21蛋白表达无明显变化。
- Compared with A549cells,the pHi of c ells co-transfected antisense genes was remarkably decreased(P<0.05),while lactate content was remarkab ly increased(P<0.001). The cell cycle was blocked at G 0 -G 1 period. 与A549细胞比较;联合转染反义基因的细胞pHi降低、乳酸显著升高(P<0.;001);细胞周期阻滞在G0-G1期。
- Construction and Expression of Mouse DOC-1R Antisense Gene Vector 小鼠DOC-1R反义重组载体的构建及表达的研究
- Keywords Adenoviridae;Lymphokines;Endothelial growth factor;Antisense gene; 腺病毒科;淋巴因子;内皮生长因子;反义基因;
- Keywords OPN;Viral Myocarditis;CoxsackievirusB3;Antisense gene therapy; 骨桥蛋白;病毒性心肌炎;柯萨奇B3病毒;反义基因治疗;
- Relation of c-jun antisense gene transfection and cardiomyocyte apoptosis following hypoxia and burn serum treatment c-jun反义基因转染与缺氧复合烧伤血清处理心肌细胞凋亡关系的研究
- The antisense gene of growth factor receptor reversing the malignant phenotype of human hepatoma cells 生长因子受体反义基因逆转肝癌细胞的恶性表型
- Generation of a rice mutant library by shotgun antisense gene silencing and mutant screening 利用反义基因沉默策略构建水稻突变体库及突变体筛选
- Effect of c-jun Antisense Gene on Proliferation of Rat Vascular Smooth Muscle Cells 反义癌基因c-jun对大鼠血管平滑肌细胞增殖的影响
- The Study of Mechanisms and Antisense Gene Therapy of Immune Escape Through Fas/FasL Route in Neoplasms 肿瘤Fas/FasL途径免疫逃逸机制探讨及反义基因治疗对策的实验研究
- Keywords heparanase;sense and antisense gene;fluorescent eukaryotic expressing vector;transfection; 肝素酶;正、反义基因;荧光真核表达载体;转染;
- Keywords Monocyte chemotactic protein 1;Gene therapy;Antisense gene;Vein graft;Cationic lipids;Nanoparticle; 单核细胞趋化蛋白1;基因治疗;反义基因;静脉移植;阳离子脂质体;纳米粒子;
- Preliminary Study on the Expression of Survivin and the Combination Therapy with It's Antisense Gene and Recombinant Fusion Protein of Bladder Cancer 在膀胱癌的表达及其反义基因联合重组融合蛋白治疗膀胱癌的实验研究
- Effect of c-fos antisense gene transfection on protection of cardiomyocytes following hypoxia and burn serum treatment in rats c-fos反义基因转染对缺氧复合烧伤血清处理大鼠心肌细胞保护作用的实验研究
- Molecular Mechanism of c-jun Antisense Gene Transfection in Protecting Cardiomyocyte from Injury of Hypoxia and Burn Serum Treatment c-jun反义基因转染对缺氧复合烧伤血清处理心肌细胞保护作用的分子机制研究
- INHIBITION OF HUMAN HEPATOMA GROWTH AND N-ras EXPRESSION IN MICE BY PSEUDOTYPE RETROVIRUS CONTAINING HUMAN N-ras ANTISENSE GENE 含人N-ras反意基因的假型逆转录病毒对裸小鼠体内人肝癌移植瘤生长和N-ras表达的作用
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- 深远海浮式风电平台 - deep-sea floating wind power platform
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- 京雄高速公路 - Beijing-Xiongan expressway
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- 农业及相关产业增加值 - the added value of agriculture and related industries