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- antigenic epitopes prediction 溶细胞素
- Keywords Vibrio vulnificus cytolysin;antigenic epitopes prediction;phage display;T cell epitope;B cells epitope; 创伤弧菌;溶细胞素;噬菌体展示;B细胞表位;T细胞表位;
- To predict antigen epitopes on B cell of VP2 of canine parvovirus 2b subtype(CPV-2b),the VP2 gene of CPV-2b was cloned and sequenced. 对犬细小病毒2b亚型衣壳蛋白VP2基因进行了克隆、测序,并用分子生物学软件DNAStar对VP2基因的推导氨基酸序列进行了表位分析。
- Because the exact antigenic epitopes responsible for immunity are not well understood, whole-cell vaccines are best. 因为还不清楚决定免疫力的具体抗原决定部位,所以全细胞疫苗是最好的。
- By the host machinery,the glycosylation of these proteins protect potential protein antigenic epitopes on the virus. 它使病毒粒子具有高度糖基化的表面,帮助HIV逃避人体免疫细胞识别和攻击。
- Prokaryotic expression of structural domains of the Newcastle disease virus fusion protein and analyses of their antigenic epitopes. 新城疫病毒F蛋白结构域基因原核表达与抗原表位分析
- Seven synthesized peptides were produced by mimicking the antigenic epitopes of the S-protein in SARS-CoV with computer techniques. 利用计算机技术模拟SARS冠状病毒S蛋白的抗原表位并合成了7条多肽,研究合成肽与SARS患者早期血清的反应性。
- The antigenic epitopes recognized by WM53 are located in the AAR 17-60 of CD33 antigen. The antigenic epitopes recognized by M195 are located in the AAR 170-262 of CD33 antigen. 结论HIM3-4、WM53、M195识别的CD33抗原表位分别位于115~170、17~60、170~262氨基酸。
- Objective:To approve there are commen antigen epitopes and cross-reaction lying between oilseed rape(Brassica campestris L. 目的:证实油菜花粉和蒿草花粉存在共同抗原决定簇和交叉反应。
- Objective To obtain the antigenic epitopes which can affinitive bind to theHCV(hepatitis c virus) polyclonal antibodies by using a phage 12-mer peptide libraryand to test the efficiency of converse biopannning by using negative serum. 目的筛选噬菌体展示随机12 肽库中可以与HCV 抗体阳性的血清特异性结合的序列,在HCV 表达的蛋白分子上找到这个抗原表位, 分析其序列、结构特点与功能的关系。 同时检验用阴性血清逆向筛选是否能提高筛选效率。
- Conclusion: 1.The prediction of antigen epitope is accurate. High titer antibodies of anti-GPBB were obtained with the compound peptide immuning animals. 结论:1.本文以多参数预测的抗原表位比较准确,以此为根据合成的复合肽抗原免疫动物制备了高效价的抗体,抗体即可与天然抗原反应,也具有高度的特异性。
- The expressed fusion proteins could be recognized by antibodies of rabbit anti RESA peptide EENVEHDA by Western blotting,indicating that the fusion proteins harbored the antigenic epitopes of Plasmodium falciparum . 免疫印迹分析显示表达产物可与兔抗恶性疟原虫RESA多肽抗原的抗体发生特异性免疫反应,提示融合蛋白中含有恶性疟原虫抗原位点。
- Two fusions genes, CTB/ATE and CTB/AWTE, which contain sequences coding for multiple antigenic epitopes of malaria Plasmodium falciparum and cholera toxin B subunit (CTB) gene used as a carrier were constructed. 以霍乱毒素B亚基(CTB)基因为载体,构建了含不同抗原表位的恶性疟原虫的融合基因CTB/ATE和CTB/AWTE。
- The aboe-mentioned CTL epitope prediction results exist certain deiation, due to difference of their database source of building matrix motifs and form of scoring function. 上述这些CTL表位预测程序,依据其建立矩阵的数据来源和打分函数形式的不同,预测结果也会有一定偏差。
- The aboe-mentioned CTL epitope prediction results exist certain deiation, due to difference of their database source of building matrix motifs ... 上述这些CTL表位预测程序,依据其建立矩阵的数据来源和打分函数形式的不同,预测结果也会有一定偏差。
- Both of the common methods of experimental determination and theorical prediction for identifying T cell antigen epitope and the methods of T cell epitope analysis were summarized. 综述了近年来实验确定和理论预测T细胞蛋白质抗原表位的常用方法,以及T细胞抗原表位分析的研究方法。
- Seven Moth recognized different antigen epitopes of AIF from different tissues, butMcAb 5c3 and 4d2 recognized the same antigen epitope of AIF. 抗AIFMcAbs均与各自AIF分子上不同抗原决定簇结合,其中针对不同组织AIF的McAb5c3和4e2作用于同一抗原决定簇。
- Some non-NPC neoplasms being demonstrated BAE-5 positivity may be due to the presence of EBV EA-R antigenic epitope or polypeptides simulating the structure of EA-R. 一些非鼻咽癌肿瘤能与BAE-5起阳性反应,可能是由于这些肿瘤细胞中也有EB病毒早期抗原存在或者可能存在与EA-R抗原决定簇相类似结构的多肽而引起交叉反应。
- Results:The new gene encoding the antigen epitope of SARS-CoV S protein was designed and synthesized s... 结论:可以重新设计新基因产生新型候选重组疫苗。
- I can predict something with great accuracy. 我能很准确地预测某事。