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- Because thymic dendritic cells are the potent antigen presenting cells in the thymus, they must play an important role in thymic negative selection. 胸腺树突状细胞作为胸腺内功能强大的抗原呈递细胞,在阴性选择中必定发挥着不可忽视的作用。
- Relationship between costimulatory molecule CD80/CD86 expressing on antigen presenting cells and spontaneous abortion. 抗原递呈细胞表面共刺激分子CD80/CD86表达与自然流产的关系
- Dendritic cells (DCs) are one of the most potent antigen presenting cells (APCs). 树突状细胞(DC)是目前已知的功能最强的专职抗原提呈细胞。
- HLA-DR~+ antigen presenting cells(APC) reduced remarkably in the SARS spleen white pulp. 脾白髓中HLA-DR+抗原呈递细胞明显减少。
- Dendritic cells are the most powerful antigen presenting cells,which plays very important effect in immune system. 树突状细胞是体内最强的抗原呈递细胞,在免疫系统中发挥着重要的作用。
- The first signal is specific, which T cell receptor could recognize and bind MHC molecule by antigen presenting cells. 第二信号是由T细胞上的CD28与抗原呈递细胞上的B7分子的结合而提供的。
- Aim: To explore the distribution of antigen presenting cells(APC) in mouse iris-ciliary body (ICB) after allogeneic bone marrow transplantation (BMT). 目的:观察异基因骨髓移植后小鼠虹膜睫状体内抗原递呈细胞(APC)的分布情况。
- Through the T cells receptors (TCRs), CTLs can recognize the MHC class I-associated peptides complex on surface of the antigen presenting cells (APCs) such as malignant cells. CTL通过其T细胞受体特异性识别抗原提呈细胞(antigen-presenting cells,APCs)(如肿瘤细胞)表面的主要组织相容性复合体(major histocompatibility complex, MHC)-I类分子-肽复合物,然后自身得以活化,并最终通过多种机制杀死靶细胞。
- Recently, dendritic cells (DCs) are found to play a dual role in the immunological system. Apart from inducing immune response as antigen presenting cells (APCs), DCs can also induce central and peripheral tolerance. 近年来，树突状细胞(dendritic cells,DCs)被发现在免疫系统中扮演着双重角色，除作为抗原提呈细胞(antigen presenting cells,APC)诱发免疫反应外，还能诱导中枢或周围性免疫耐受。
- K562-B7-DCs induced by GM-CSF, IL-4 and IL-12 have the function of antigen presenting cells, and can help T lymphocyte to execute the anti-tumor effect, therefore enhancing anti-tumor immunity. 细胞因子联合诱生的K562-B7-DC能有效的执行其抗原提呈功能,同时协同T淋巴细胞发挥其抗肿瘤免疫作用。
- In recent years, attenuated intracellular bacteria have elicited great concerns as vehicles for DNA vaccine delivery. DNA vaccines can be directly delivered into antigen presenting cells (APCs) by this means. 近年来，应用减毒胞内菌作为DNA疫苗的运送载体受到广泛关注，由于该途径可以通过减毒胞内菌将DNA疫苗定向运送至抗原提呈细胞(APCs)内，因而大大提高了DNA疫苗的摄入效率。
- This review focuses on recent advances in understanding the CD4+ CD25+ regulatory T cells, chemokine and receptor, chemokine receptor expressing on CD4+ CD25+ Tr cells and the attraction of these cells by antigen presenting cells (APCs). 了解CD4+CD25+Tr细胞、趋化性细胞因子、趋化性细胞因子受体和表达于CD4+CD25+Tr细胞上的趋化性细胞因子受体以及它们与不同的抗原提呈细胞(APCs)之间的作用的最新研究进展十分必要。
- DNA vaccine delivered by attenuated intracellular bacteria can be directly delivered into special antigen presenting cells (APCs), so it improves the efficiency of DNA vaccine to a great extent. 运用减毒胞内菌运送DNA疫苗能够将DNA直接运送到专业性抗原提呈细胞(APC)内,大大提高了DNA疫苗的摄入效率。
- Dendritic cells (DCs) are the most potent antigen presenting cells (APCs) that prime naive T lymphocytes and active antigen specific cytotoxic T lymphocytes(CTLs), which makes DC a promising tools for immunotherapy of cancer . 树突状细胞(Dendritic Cells,DCs)作为功能最强的抗原提呈细胞，在恶性肿瘤的免疫治疗中起着重要的作用。
- Tumor cells may escape immune surveillance due to lack of costimulatory singal which is essential for the activation of host immune system. Effective activation of T lymphocytes requires two signals from antigen presenting cells (APCs). 肿瘤免疫学研究表明：肿瘤逃避机体免疫监视的机制之一可能是因为肿瘤细胞表面缺乏使T细胞完全活化的共刺激信号。
- The abnormal expression of CD28 and CD80 on PBMC in patients with active SLE suggests an abnormal signal pathway between antigen presenting cells(APCs) and T cells in SLE patients. SLE患者外周血T细胞及APC间存在异常的CD28－CD80。
- Expression of IDO in dendritic cells (DC),the most powerful or "professional" antigen presenting cells,can suppress T-cell responsiveness via influencing the phenotype and function of DCs. 而树突状细胞(DC)是专职的抗原提呈细胞,IDO在其内的表达可影响DC的表型和功能,进而抑制T细胞的免疫反应。
- B7 transfected CHO cells were used as artificial antigen presentation cells (APCs) in MLR to exclude the effects of other costimulatory molecules. 为了排除其它粘附分子的作用 ,应用联合转染DR7或 (和 )B7分子基因的CHO细胞系作为人工抗原递呈细胞 (APC)介导混合淋巴细胞反应 (MLR)。
- If antigen present cells (APCs) provide MHC-peptides only, do not present costimulatory signals such as CD80 and CD86 to T lymphocytes at the same time, T lymphocytes will became anergy, immune tolerance will be induced. 如果抗原提呈细胞(antigen present cell，APC)只提供MHC-抗原肽复合物而不提供CD80、CD86等共刺激信号，将使淋巴细胞无能，诱导免疫耐受。
- As we all know, antigen recognition. procession, presentation and T cells pulsing and activating all rely on the participationof antigen presenting cells (APCs). 抗原的识别、加工、提呈以及T细胞的致敏、激活和扩增都依赖于抗原递呈细胞（APCs）的参与。
