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- allele linkage analysis 等位基因连锁反应
- Another important method of linkage analysis is the Affected Sib Pair (ASP). 连锁分析的另一种重要统计方法是生病同胞对法(ASP)。
- Methods The parameter linkage analysis of the small pedigree data was used. 方法运用小家系资料连锁分析参数的方法。
- RFLP Linkage Analysis and deletion analysis in one family with BMD and two families with DMD. 一个BMD和二个DMD家系的RFLP连锁分析和缺失分析
- This information is valuable both as a prelude to linkage analysis, which generally assumes Mendelian transmission. 这一信息有利于进一步所做的连锁分析。
- Objective To identify the disease locus in X-linked retinitis pigmentosa (RP) families using genetic linkage analysis. 目的应用遗传连锁分析方法对X连锁型视网膜色素变性家系进行分析,定位其致病基因的所在位点。
- Selection is practically ubiquitous during marker-QTL linkage analysis with an experimental population. 从实际角度看，选择在用于标记-QTL连锁分析的实验群体中是较普遍存在的。
- Objective To identify the disease locus in X-linked retinitis pigmentosa(XLRP) families using genetic linkage analysis. 目的应用遗传连锁分析方法对X连锁型视网膜色素变性家系进行分析,确定其致病基因的所在位点。
- Meanwhile,the method of gene linkage analysis and that of using oligonucleotide probe are compared. 同时将基因的连锁分析法与寡核苷酸法进行了比较。
- This STR linkage analysis can identify the molecular defect of PWS cases quickly and accurately. STR连锁分析是一种可准确诊断PWS并明确其分子缺陷类型的好方法；
- But no pathogenetic gene has been cloned. To refine the location of CMN, we had research on a Chinese pedigree of CMN through genescan and linkage analysis. 我们拟应用基因组扫描技术，通过连锁分析对一个来自于浙江温州的CMN家系进行相关致病基因的染色体定位研究。
- Recently, with using of whole genome genotyping and linkage analysis, some chromosome regions have been related to human dermatoglyphic patterns. 特别是最近几年，通过全基因组基因分型和连锁分析，在染色体上得到了一些和肤纹特征相关的基因候选区域。
- Objective To study the clinical application value of genetic linkage analysis for bronchial asthma with two STRs-D5S436 and D5S658. 目的探索短串联重复序列-D5S436和D5S658在支气管哮喘家系连锁分析中的应用价值。
- Haplotype and linkage analysis indicate that the Ashkenazi haplotypes is not associated with HMPS in Singapore Chinese families,which suggests genetic heterogeneity. 单倍型及遗传连锁分析提示,Ashkenazi单倍型与华人HMPS无关,两者存在遗传背景的差异性。
- The two-locus, non-parametric linkage analysis (NPL), maximum LOD score and transmission/disequilibrium test (TDT) with GENEHUNTER program were used in this study. 统计采用GENEHUNTER软件包两点非参数连锁（NPL）分析、计算优势对数记分(Lod)值及传递不平衡检验（TDT）。
- First half focuses on human genetics and molecular biology, covering fundamentals of pedigree analysis, linkage analysis, molecular cloning, and gene analysis as well as ethical/ legal issues, all in the context of an auditory disorder. 前半段会著重于人类遗传学与分子生物学，涵盖家族系谱分析、锁分析、子选殖、因分析与道德法律议题的基础概述，并且皆以听觉系统疾病为例来说明。
- Simulation study and real data analysis were performed using SAS/IML software, and the validity and practicability of Bayesian method in genetic linkage analysis were thus verified. 用编制的SAS/IML程序进行了模拟研究和实例分析，验证了贝叶斯方法在遗传连锁分析中的有效性和实用性。
- Model-independent sib-pair linkage analyses and tests of association were performed to analyze the genetic effects of the exon 12 polymorphism. 个体模型同胞配对后，通过进行连锁分析和关联实验，来分析外显子12多态现象的遗传效应。
- Thus, it is necessary to investigate the impacts of selection upon linkage analyses in order to obtain unbiased estimates of QTL position and effect. 为获得QTL位置及其效应的无偏估计，有必要研究选择对连锁分析实验所造成的影响。
- Aim:To set up a method of prenatal diagnosis of classic phenylketonuria ( PKU) by linkage analysis of the short tandem repeat(STR) in intron 3 linked to the phenylalanine hydroxylase (PAH) gene. 目的:建立一种利用苯丙氨酸羟化酶(PAH)基因内含子3中短串联重复序列(STR)多态性连锁分析进行经典型苯丙酮尿症(PKU)产前诊断的方法。
