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- Objective: To determine whether isoflurane attenuates myocardial stunning, and whether the myocardial protection of isoflurane is mediated by adenosine receptor subtypes A1. 实验一异氟醚对顿抑心肌的保护及腺苷A_1受体拮抗剂的影响摘要目的:观察异氟醚减弱心肌顿抑的作用并确定腺苷A_1受体是否参与该保护过程。
- John A. Auchampach and Roberto Bolli Adenosine receptor subtypes in the heart: therapeutic opportunities and challenges 心脏中腺苷受体亚型:治疗机会与挑战
- Objective: To study the protecting effect of delayed preconditioning with A1 selective adenosine receptor agonist in donor heart preservation. 目的:探讨腺苷A1受体激动剂延迟预处理对大鼠心脏的保护效果。
- Alteration of cardiac alpha1-adrenergic receptor subtypes in cardiac insufficient rat. 心功能不全大鼠心脏1肾上腺素受体亚型的改变。
- No change in the mRNA levels of these receptor subtypes was observed on the contralateral side. 上述受体亚型在非损伤侧脊髓背角内的表达水平均无变化。
- Objective:To study the method of aminophylline as an adenosine receptor antagonism on the victims of cardiac arrest refractory to epinephrine. 目的:探讨在肾上腺素无效的心脏停搏患者中应用腺苷受体拮抗剂氨茶碱的方法。
- As dipyridamole did not affect glucose uptake, peripheral adenosine receptor antagonism did not appear to contribute to the mechanism of insulin sensitivity. 由于潘生丁并不影响糖的吸收,因此外周腺甘受体拮抗似乎不影响胰岛素敏感性。
- Abstract: As a kind of purine nucleoside,many physiological and pathological actions of adenosine are personalized by the combination with its corresponding adenosine receptor. 摘要: 作为一种嘌呤核苷,腺苷的多种生理及病理作用均是通过与其相应的受体结合来体现的。
- Subsequent generations of SSRIs addressed some of those issues by building in blockers of certain serotonin receptor subtypes to eliminate unwanted drug actions. 其后的几代SSRI藉由建立特定血清张力素受体亚型的受体阻断剂,消除了不要的作用,而解决了一些问题。
- Furthermore, PTP1B deletion significantly reduced gene expression of 3 1-adrenergic receptor subtypes, consistent with blunted constriction to phenylephrine. 此外PTP1B缺乏明显减少31-肾上腺受体亚型基因表达,与对苯福林收缩反应迟钝有关。
- The relationship between the mRNA expression of LPA receptor subtypes and the myocardial hypertrophy and apoptosis in AMI rat and in AMI rat treated with carvedilol were studied. 提示LPA三种受体亚型在心肌重塑过程中有重要作用,卡维地洛的治疗机制可能与LPA受体信号通路相关。
- D and 5-HT1F receptor subtype mRNAs were present in the DRGs. 蜜蜂毒致痛后大鼠腰段脊髓和 DRG内 5-HT;
- This finding suggests ways to improve anxiolytics and to develop drugs for other neurological disorders based on their specificity for GABA(A) receptor subtypes in distinct neuronal circuits. 这个发现指明了改善舒缓焦虑的方法,并得以为在不同的神经元回路中,特定之GABA(A)受体子类的其他神经方面失调,开发新药。
- Y2 receptor, one of the two early recognized major receptor subtypes of neuropeptide Y (NPY) was considered to be involved in multiplicate biological and pathological functions induced by NPY. Y2受体亚型是早期发现的NPY的两种主要受体亚型之一,参与NPY所介导的多种生理和病理功能。
- This study was designed to test the hypothesis that blockade of central nervous system (CNS) adenosine receptors may explain the beneficial effect of caffeine on fatigue. 此研究的目的是验证下述假设:咖啡因对解除疲劳的正面作用是通过阻断中枢神经系统(CNS)的腺苷受体实现的。
- AIM To observe the distribution of 5 HT 5A receptor subtype (5 HT 5A R) in the rat nervous system. 目的 观察大鼠神经系统内 5 - HT5A受体亚型 (5 -HT5AR)的定位分布 .
- Your pupils dialate, your blood pressure rises, as a response your livers dumps more sugar into your bloodstream.The adenosine receptors in your brain are now blocked preventing drowsiness. 由于肝脏将大量糖分转化到你的血液中,你的瞳孔放大,血压上升,你大脑中的腺苷接受器就会抑制你的睡意。
- SNI also resulted in a significant increase in the mRNA expression of 5-HT_7 receptor subtype at 1 d, then maintained at a high level to 28 d. 5-HT7 受体亚型mRNA的表达在术后 1d时即显著升高,一直维持高水平的表达至28d。
- Objective To investigate the role and mechanism of bombesin receptor subtype 3(BRS-3) in the proliferation and protection against injury of human brochial epithelial cells(HBECs). 目的:研究蛙皮素受体亚型-3(bombesin receptor subtype-3,BRS-3)激活对人支气管上皮细胞(hum an broch ial ep ithelial cells,HBECs)增殖的影响及对HBECs抗损伤的保护作用,并探讨其初步机制。
- AIM To study the changes and effects of metabotropic glutamate receptor subtype 2 (mGluR2) in diffuse brain injuries (DBI) coupled with secondary brain insults (SBI) in rats. 目的 研究弥漫性脑损伤 (diffusebraininjury;DBI)及其合并二次脑损伤 (secondarybraininsults;SBI)后大鼠脑皮层代谢性谷氨酸受体 2亚型 (mGluR2 )的变化及其意义 .