- Objective: To establish a method for determination of the residual solvents in ade fovir dipivoxil.
- Domestic adefovir dipivoxil(daiding made in China)10 mg dail orally were administered for 52w in group B(46 cases).
- In this paper the synthesis of adefovir dipivoxil was introduced,the study and the improvement of the process also discussed.
- Fufangbiejiaruanganpian united Adefovir Dipivoxil treatment of chronic hepatitis B could significantly improve the effect of anti-fibrosis.
- One of the two had hepatocellular carcinoma and died of hepatic failure at week 125; the other received adefovir dipivoxil (Hepsera) and is doing well.