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- Dihydroartemisinin is the main active metabolite of artemisinin derivatives. 青蒿素衍生物的主要活性代谢产物是二氢青蒿素。
- Stavudine is phosphorylated by cellular kinases to the active metabolite stavudine triphosphate. 司他夫定通过细胞激酶磷酸化，形成司他夫定的三磷酸盐而发挥抗病毒活性。
- Objective: To investigate the facile method for preparation of albendazole sulfoxide,an active metabolite in vivo . 目的:探索阿苯达唑体内活性代谢物亚砜的制备方法。
- Acitretin, an active metabolite of etretinate, is as effective as etretinate in the treatment of psoriasis. 阿维A是阿维A酯的活性代谢物，治疗银屑病时与阿维A酯有相同的效应。
- Isosorbide mononitrate is an active metabolite of isosorbide dinitrate and exerts qualitatively similar effects. 单硝酸异山梨酯是二硝酸异山梨酯的一种活性分解物，并表现出同样相似的作用。
- OH)2 VD3 is an active metabolite of vitamin D3 and always thought to be a balancer in the homeostasis of calcium and phosphorus. 2VD3是维生素D3在体内的活性代谢产物,通过与细胞核上的受体结合发挥着维持钙磷平衡的作用。
- The new type of antihistamine,fexofenadine,an active metabolite of tefanadine,was introduced with its pharmacology and clinical application. 介绍了新型抗组胺药非索非那定的药理作用及临床应用。
- The study showed that 4-OH-P is an important active metabolite of PPL and one of thepossible factors causing the considering variations in the response to PPL in Chinese people. 本文同时建立的PPL及4－OH－P药代一药效学统一模型将有助于指导临床合理用药和药效学定量研究。
- HPLC method with fluorescence detection for determination of dextromethorphan (1) and its active metabolite, dextrorphan (2) in human plasma was presented. 建立了简便、准确、灵敏的反相高效液相色谱-荧光检测法测定人血浆中右美沙芬和活性代谢物去甲右美沙芬的血药浓度。
- OBJECTIVE To develop an HPLC-fluorescence metho d for determination trans tramadol and its active metabolite, O-demethyltrama dol (M1), in human serum, and study the pharmacokinetics. 目的 :建立人血清中反式曲马多 (transT)及其活性代谢物反式氧去甲基曲马多 (M 1)同时测定的HPLC荧光分析法并研究其人体药动学。
- Acitretin is a second generation aromatic retinoid, and is the active metabolite of etretinate.Acitretin has a shorter terminal elimination half-life and higher bioavailability than etretinate. 阿维A为第二代维A酸,是阿维A酯的代谢活性酸,具有较高的生物利用度及较短的半衰期,已广泛治疗各种角化性皮肤病,而这些角化性疾病大多是遗传性疾病。
- For drugs with an active metabolite, the therapeutic consequence of first-pass metabolism depends on the contributions of the drug and the metabolite to the desired and undesired effects. 对于那些生成活性代谢物的药物来讲;经过首过代谢的治疗上的重要性取决于药物和代谢物所引起的期望的和非期望的效应.
- OBJECTIVE: To compare the antihistamine activity of desloratadine, the active metabolite of loratadine, with that of cetirizine in the skin wheal-and-flare responses during 24 hours. 目的：比较地氯雷他定（氯雷他定的活性代谢产物）与西替立嗪在24小时内对皮肤风团及潮红应答的治疗效果。
- Keywords camptothecin;active metabolite;QSAR;anti-tumor; 喜树碱;代谢活性物质;构效关系;抗肿瘤;
- Keywords Prulifloxacin;The active metabolite UFX;Pharmacokinetics; 普卢利沙星;活性代谢物UFX;药动学;
- Pharmaceuticals and pharmaceutically active metabolites have been increasingly detected in field samples. 在环境水体中不断监测到医药类污染物及其活性代谢产物。
- When sedating the geriatric patient, the agent of choice should have a short half-life, with minimal active metabolites and limited side effects. 当给老年患者镇静时应该选择半衰期短、代谢活性物少和副作用少的药物。
- The orient has been playing an active role in the world economy. 亚洲一直在世界经济中发挥积极作用。
- He is an active member of the school's stamp club. 他是学校集邮俱乐部的一名活跃会员。
- An active volcano may explode at any time. 活火山随时都有可能爆发。
