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- AIM: To study the effect of signal transducer and activator of transcription 6 (STAT6) on airway inflammation of rats with asthma. 目的:探讨信号转导子和转录激活子6(STAT6)及其mRNA在哮喘大鼠气道炎症中的作用。
- Objective To study the modulation of budesonide(BUD) on signal transducer and activator of transcription 6 (STAT6) and its gene expression in the rat model of asthma. 目的研究布地奈德(BUD)对支气管哮喘大鼠支气管信号转导子和转录激活子6(STAT6)基因和蛋白表达的调控作用。
- Objective:To study the effect of inhibiting janus kinase/signal transducer and activator of transcription(JAK/STAT) pathway on acute liver injury in rats with postburn Staphylococcus aureus sepsis. 目的:研究JAK激酶/信号转导和转录激活子(JAK/STAT)通路对烫伤后金黄色葡萄球菌(金葡菌)感染致严重脓毒症大鼠肝损害的影响。
- Members in this pathway include the Janus kinases (JAKs) family containing JAK1, JAK2, JAK3 and TYK2 and the STATs (signal transducer and activator of transcription), which contain STAT1 to STAT6. 然而它所影响范畴包括了细胞增生、细胞命运的决定、组织的发育以及免疫系统反应。哺乳类动物中,JAK家族有JAK1, JAK2, JAK3 和TYK2,STAT家族则有STAT1-6。
- Objective: To observe the expression of signal transducer and activator of transcription 3(STAT3) and its activity in the spinal nerve and their nerve cell bodies. 目的 :研究脊神经及其胞体中信号传导子和转录激活子 3( STAT3)的表达及其活化程度。
- Like runners passing the baton, the phosphate-tagged enzymes become activated from a dormant state and stimulate the activity of transcription factors. 就像接力赛跑选手交棒一般,标记上磷酸分子的酵素会从不活化态变成活化态,并且刺激转录因子的活性。
- Objective To explore the activation and function of Janus protein-tyrosine kinase (JAK)/ signal transducer and activator of transcription (STAT1) signal transduction pathway in kidney,lung and brain of MRL/lpr mice. 目的探讨Janus蛋白酪氨酸激酶(JAK)/信号转导和转录激活子1(STAT1)信号转导途径在MRL/lpr狼疮鼠肾脏、肺脏、脑等不同器官中的活化和作用。
- Novel oncogene with kinase-domain (NOK) can activate multiple mitogenic signaling pathways including the janus kinases (JAK) and signal transducer and activator of transcription proteins (STAT). 摘要NOK能激活包含JAK-STAT信号通路在内的多种促细胞有丝分裂信号通路。
- Objective To investigate the expression levels of signal transducers and activators of transcription(STATs) in the lung tissue of hypoxic pulmonary hypertension (HPH) rat models. 目的 通过观察大鼠常压缺氧肺动脉高压模型肺组织信号传导与转录活化因子(STATs)的表达水平 ,探讨其在低氧性肺动脉高压 (HPH)形成过程中参与的可能机制。
- BACKGROUND & OBJECTIVE: Cyclooxygenase-2 (COX-2) and signal transducers and activators of transcription (STAT) are closely correlated to the genesis of tumors. 背景与目的:研究表明,环氧化酶-2(cyclooxygenase-2,COX-2)及信号转导和转录活化因子(signal transducers and activators of transcription,STAT)的活化均与肿瘤的发生、发展密切相关。
- Finally, oxidants are involved in intracellular signalling pathways leading to activation of transcription factors and thus influencing gene transcription. 最后,氧化物通过干预细胞信号转导途径,导致转录因子的激活,而影响基因的转录。
- signal transducer and activator of transcription 信号传导子及转录激活子
- signal transduction and activator of transcription 信号传递与转录激活因子
- signal transducer and activator of transcription 6 信号转导子和转录激活子6
- Signal transducer and activator of transcription 1 信号转导及转录激活子-1
- Signal transducer and activator of transcription 5 信号转导及转录激活子5
- Singnal transducer and activator of transcription 3 信号转导和转录激活因子3
- signal transducers and activator of transcription 1 信号转导与转录激活因子1
- signal transducers and activator of transcription 6 信号转导与转录激活因子6
- Signal transducer and activator of transcription 3 信号传导与转录激活因子3