- Although S.sobrinus was less frequently detected in human oral cavities than S.mutans, it has been described as more virulent than S.mutans due to its high acidogenicity and acid tolerance.
- Acid tolerance is one of the main cariogenecities of Streptococcus mutans, especially its acid tolerance response, is regarded as a significant factor for its life and cariogenecity.
- In the test of acid tolerance,the aciduric ability of strain PR389 under low acidic(pH3.8) was restrained by antibiotic chloramphenicol. It was speculated that special proteins in the cells of PR389 could be induced and synthesized in acidic environment.
- Acid production by Lactococcus lactis subsp, lactis is followed by additional acid production associated with the growth of more acid tolerant organisms such as Lactobacillus.
- They have a high tolerance of acid conditions.