Zaleplon,a new sedative hypnotic drug was synthesized from acetophenone by nitration,reduction,acylation,condensation,hydrocarbylation,and cyclization.

• 以苯乙酮为原料,经硝化、还原、酰化、缩合、烃化、环合反应合成了新型镇静催眠药扎来普隆,总收率为221%25。