Women who had used estrogens combined with sequential progestins had a 54% increased risk of developing epithelial ovarian cancer compared with women who had never used this type of therapy.

• 同从未使用过这些疗法的妇女相比，使用雌激素并定期服用孕酮的妇女，发展为上皮卵巢肿瘤的危险率增加了54%25。