When SATB1 expression is reduced in the metastatic cell lines, they too form the kind of polarized, uniform acinar structures found in normal mammary epithelial cells.

• 体外试验中，正常细胞形态相似，腺泡结构排列整齐，然而那些高侵袭的上皮细胞系的结构紊乱并且失去极性。