We measure the activity of Na/K ATPase and examine the gene ATP1A1 in type 2 diabetes mellitus by PCR-RFLP to investigate the relationship between Na/K ATPase activity and ATP1A1 gene polymorphism and diabetic neuropathy.

• 我们通过检测Na/K ATP酶的活性及应用PCR-RFLP技术研究大连地区汉族人Na/K ATP酶活性及ATP1A1基因多态性与糖尿病周围神经病变的关系,旨在阐明糖尿病周围神经病变发生的遗传因素,在糖尿病人群中筛选糖尿病周围神经病变易感个体,以便早期防治。