We also found upregulated HLA-A heavy chain in high HLA class I expression cell lines QGY7701 and BEL7405 and lacked the expression of LMP2 and LMP7 in low HLA class I expression cell line BEL7404 by real-time PCR.

• 在HLA I类分子表达下调的细胞系BEL7404中,HLA重链、轻链及TAP分子均表达正常,存在蛋白酶体复合物亚单位LMP2表达减少,LMP7表达缺失。