WT1 mRNA expression was revealed in K562,HL?60 and TF?1 cell lines, 21 of 25 (84%) AML patients,8 of 11 (73%) ALL patients,2 CML patients in blast crisis and 1 of 7 CML patients in accelerated and chronic phase.

 
  • K562、HL-60及TF-1三株白血病细胞系均高度表达WT1,而U937细胞系未测到WT1。 急性髓系白血病(AML)25例中21例、急性淋巴细胞白血病(ALL)11例中8例、慢性粒细胞白血病(CML)急性变者2例、慢性及加速期CML患者7例中1例WT1表达阳性。
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