Using EPR spin labelling 5 NS, 16 NS (for fatty acids) and MSL (for proteins), the changes in lipid fluidity and protein conformation in the ghost erythrocyte membrane of rat treated by endothelin have been studied.

 
  • 以大鼠红细胞膜为研究对象,以脂肪酸自旋标记物5NS,16NS插入膜脂,蛋白自旋标记物MSL标记膜蛋白,观察内皮素(ET)损伤后膜脂流动性、膜蛋白构象的变化及金属硫蛋白(MT)抗ET保护生物膜作用。
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