Tumor necrosis factor (TNF)-converting enzyme (TACE) has emerged as a potential therapeutic target in the areas of arthritis, cancer, diabetes and HIV cachexia.

• 摘要肿瘤坏死因子转化酶(TACE)已经成为治疗关节炎、癌症、糖尿病和HIV恶病质等疾病的一种潜在新靶点。