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- Tripeptide aminopeptidase 三肽氨肽酶
- Objective:To search for a protocol for synthesis of tripeptide. 目的:设计出一种合成三肽的方案。
- Arm: to search for a protocol for synthesis of tripeptide. 目的:设计出一种合成三肽的方案;
- Glutathione is a tripeptide that must be manufactured within the cell. 谷胱甘肽是由三种胺基酸所组成的三肽,必须在细胞内制造。
- Objective: to investigate the variation and significance of urinary alanine aminopeptidase(AAP) in nephrotic syndrome . 目的 :探讨原发性肾病综合征病人尿中丙氨酸氨基肽酶 (AAP)活性变化及其临床意义。
- It is known that the aminopeptidase inhibitor bacitracin prevents the degradation of enkephalins in vitro. 脑啡肽脑内给药镇痛作用弱而短暂;可能是降解迅速所致。
- Objective To study the diagnositic value of serum alanine aminopeptidase(AAP) activity in fatty liver disease. 目的研究血清丙氨酸氨基肽酶(AAP)的测定对脂肪肝的临床诊断价值。
- Objective To Study the debittering effect of aminopeptidase from Bacillus subtilis on soy protein hydrolysate. 目的研究从豆腐乳中筛选到的一种枯草芽孢杆菌所产的氨肽酶脱除大豆蛋白质水解物苦味的效果。
- It is not surprising that so much research has been done, and is still being done on this small tripeptide molecule. 因此,对这种小小的三肽物质有如此多已经作过及进行中的研究也就不足为怪了。
- The aminopeptidase from Streptomyces griseus (SGAP) has been cloned and expressed in Escherichia coli. 该氨基从灰色链霉菌( SGAP )已被克隆,并表示在大肠杆菌中。
- Glutathione is an important tripeptide small molecule in organism and possesses wide physiological function. 谷胱甘肽是生物体内一种重要的三肽小分子,具有广泛的生理功能。
- Removal of the Boc protected group and coupling with Fmoc-Gly-Cl gavethe tripeptide in an overall yield of 20% (based on D-Phe). 以甘氨酸为原料,用Fmoc-OSu保护,得到Fmoc保护甘氨酸,与草酰氯反应得到Fmoc-Gly-Cl,与脱Boc的二肽偶合,得到三肽,总收率为20%25(以D-苯丙氨酸计)。
- Objective To study the adsorbability of tripeptide serine aspartic glutamic acid (SDE) for low density lipoprotein(LDL). 目的研究丝氨酰 -天冬氨酰 -谷氨酸 (SDE)负电性三肽仿生吸附剂对低密度脂蛋白 (LDL)的吸附。
- Plackett-Burman experiment shows that wheat bran, syrup and KH2PO4 have noticeable effect on the aminopeptidase productivity. Plackett-Burman实验表明培养基中麸皮、果葡糖浆、KH2PO4三种组分是影响发酵产酶的显著因素。
- Therefore, the characteristic tripeptide sequence Arg-Gly-Asp (RGD) has been attracting much attention of investigators. 因此,关于这个特有的RGD三肽序列的研究吸引了许多的学者的关注。
- To investigate the activity of serum glycylproline dipeptidyl aminopeptidase (GPDA) in patients with breast cancer and its clinical value. 探讨乳腺癌患者血清甘氨酰脯氨酸二肽氨基肽酶(GPDA)活性的变化及其应用价值。
- The target tripeptide was synthesized in ethanol/ This-HCl buffer system with Bz-Arg-OEt as acyl donor and Gly-Asp-(NH2)2 as the nucleophile. 然后以Bz-Arg-OEt为酰基供体,以Gly-Asp-(NH2)2为亲核试剂,在乙醇/Tris-HCI反应体系中,用胰蛋白酶作催化剂催化合成了目标三肽。在试验中我们发现经过pH处理过的胰蛋白酶与酶粉作为催化剂相比具有的催化活力更高,产物产率好的优点。
- Objectives:To explore the change rule and clinical value of glycylproline dipeptidyl aminopeptidase(GPDA) in tissues of esophageal and cardiac cancers. 目的:探讨甘氨酰脯氨酸二肽氨基肽酶(GPDA)在食管贲门癌组织中的变化规律。
- Bz-Arg-Gly-Asp-(NH2)2 , a precursor tripeptide of RGD was synthesized by a combination of chemical and enzymatic methods in this study. 经过反复尝试,终于探索出一条酶法和化学法结合合成RGD三肽的路线。我们利用一种新颖的化学法和酶法相结合的策略成功地合成了RGD 前体三肽Bz-Arg-Gly-Asp-(NH2)2。
- Objective To study the continuous monitoring method determining leucine aminopeptidase(LAP)and its clinical application. 目的探讨应用连续监测法测定尿亮氨酸氨基肽酶(LAP)及其临床应用价值。