Treatment of 2-aminoacetonitrile with di-tert-butyldicarbonate gave N-BOC-2-aminoacetonitrile,which was then catalyzed in the presence of ammonia and methanol to form amidine.

• 采用叔丁氧羰基(BOC)对2-氨基乙腈的氨基进行保护,在氨气的甲醇溶剂中催化形成脒,最后用无水溴化氢脱保护得到最终产物2-氨基乙脒化二溴化氢盐,经核磁鉴定为目标产物。