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- Fat-1 gene can be integrated into mouse to obtain the transgenic mouse that provides an animal model for the study of fat-1 gene. fat-1基因可整合到小鼠体内,得到的转基因小鼠为研究fat-1基因的生物学功能提供了动物模型。
- So maybe the Transgenic Mouse and the Knockout approach could be used to better understand the role of ALAD gene in the susceptibility of lead toxic effects on humans. 所以，如果能运用转基因大鼠模型和基因敲除技术，相信就能更好了解ALAD基因多态性对铅毒性易感性的影响。
- Xiong J,Zi XY,Yao YC,et al.Establishment of transgenic mouse model habouring hepatitis B virus x gene[J].Di-er Junyi Daxue Xuebao(Acad J Sec Mil Med Univ),2002,23(11):1184-1187. [4]熊俊;訾晓渊;姚玉成;等.;乙型肝炎病毒x基因转基因小鼠模型的建立及培育[J]
- In addition, the upregulation of N-RAP expression in MLP (muscle LIM protein) knockout as well as in TOT mouse (tropomodulin overexpressing transgenic mouse) might serve as an early marker for the development of DCM (dilated cardiomyopathy). 它在MLP(muscle LIM protein，MLP)敲除和tropomodulin转基因小鼠中的表达都上调，提示有可能作为扩张型心肌病(dilated cardiomyopathy，DCM)的早期标志。
- At present,lipotoxic cardiomyopathy has been found in numerous transgenic mouse models,and proves that the accumulation of cardiotoxic lipid species is associated with lipotoxic cardiomyopathy. 目前,脂毒性心肌病已在大量的转基因小鼠模型中发现,证明了有心脏毒性的脂质积聚与脂毒性心肌病是相关联的。
- The contents of this course include the mechanisms of AD, PD and ALS, the basic knowledge of AD transgenic mouse model, and the applications of cell therapy in neurodegenerative diseases. 主要内容包括AD、PD和ALS的机理、AD转基因动物模拟人类AD的实验基础、细胞治疗技术在神经退行性疾病的应用等。
- Both heterozygous Cx43 KO and CMV43~CT transgenic mice had normal hearts. 所有杂合型Cx43KO和CMV43CT基因缺陷的小鼠生后均存活,心脏病理学检测未见异常。
- Objective To detect transgenic mice of human Cathepsin_K gene by using PCR. 目的用PCR技术检测转人组织蛋白酶K基因鼠系,筛选携带目的基因的阳性小鼠。
- Then, the two recombinant genes were microinjected into the male pronuclei of fertillized mouse eggs for generating transgenic mice harbouring the introduced genes, respectively. 进而将它们分别导入小鼠受精卵雄原核,作成相应的转基因小鼠,则发现它们都失去了表达特性。
- The therapeutic vaccine could induce strong specific CTL activity in HLA-A2 transgenic mice. 其在HLA-A2转基因鼠中可诱导出强的表位特异性细胞毒性T淋巴细胞活性。
- Transgenic mice containing the human A20 gene under the control of the -myosin heay chain promoter were constructed. 在肌球蛋白重链启动子的控制下，构建了含有人类A20基因的转基因小鼠。
- "In the transgenic mice, we found two types of capsids with different densities," Yeager said. 在转基因小鼠中，研究人员发现了两种不同密度的病毒蛋白质壳。
- Chisiri FV. Hepatitis B virus transgenic mice: insights into the virus and the disease[J] .Hepatology, 1995, 22: 1816. 王宇明.;内毒素所致肝损害机理的研究进展[J]
- Transgenic mice containing the human A20 gene under the control of the -myosin heavy chain promoter were constructed. 在肌球蛋白重链启动子的控制下，构建了含有人类A20基因的转基因小鼠。
- The production of transgenic mice by pronuclear microinjection was influenced by a lot of factors. 摘要研究了移植方法和培养液对显微注射法生产转基因小鼠的影响。
- The Media Lab neuroengineering group plans to start studying such deices in transgenic mice this year. 媒体实验室神经工程学小组计划在今年用转基因小鼠来研究这一设备。
- The U.S. government is also involved in an effort to use transgenic mice in carcinogenicity testing. 美国政府也参与了一项利用转基因小鼠进行致癌实验的研究。
- None of the kidney sections from HBV transgenic mice no matter what was fed was positive for HBsAg and HBcAg. 两组HBV转基因小鼠肾组织中均未见HBsAg及HBcAg的表达。
- EBNA2 has been shown to be required for EBV-transformation of B-cells and can induce tumors in transgenic mice. 研究证实，在EB病毒所引起的B细胞转形中，EBNA2是必须的因子，且亦能在基因转殖鼠中诱发肿瘤形成。
- The DNA can then be run on a pulsed-field gel and used for microinjection to produce transgenic mice. 摘要或描述: This protocol describes the use of agarose plugs for isolation of yeast artificial chromosome (YAC) DNA.
