To understand the role of ICOS/GL50 si gnal in T-cell dependent humoral immune responses by determining the signal function in T cell proliferation and cytokine secretion as well as B cell antibody production in vitro.

• 研究ICOS/GL5 0信号在T细胞体外增殖、细胞因子分泌以及B细胞抗体分泌中的作用 ,进一步探讨该信号途径在机体体液免疫应答中的作用机制。