Three batyl alcohol derivates were synthesized from fatty acid divinyl ether with batyl alcohol, and then six mutual prodrugs were obtained by further enzymatic transetherification with nucleoside drug (ddI or acyclovir) in nonaqueous organic solvents.

• 论文研究了非水介质中酶促合成核苷和鲨肝醇的复合药物的方法; 以脂肪酸二乙烯酯利鲨肝醇获得三种鲨肝醇的单乙烯酯,进一步与去羟肌苷和阿昔洛维两种核苷类药物反应得到6种含有核苷和鲨肝醇的复合药物;