This review try to clarify the correlates between pain and depression from anatomic construct,similar change of neurotransmitter,character of clin ical situation and therapy.

• 本文试从疼痛与抑郁之间解剖结构的关联性、神经递质改变的相似性、临床表现以及治疗方面的特点对两者的关系加以综述。