This paper summarizes recent advances in chromatographic separation of chiral drugs,and introduces separating mechanisms,determining methods, reagents and applications of CDR, CMPA and CSP.

• 综述了近年来手性药物色谱分离的研究进展。对手性衍生化试剂法、手性流动相添加剂法和手性固定相法的分离机理、检测方法、试剂种类和应用等作了介绍。