This method includesGabriel condensation reaction by phthalimideso and 2-chloro-5-methylpyridine and K2CO3, then Gabriel condensationreaction product was hydrolyzed in basicity solution in the same time and hydrolytic product was distilled by vapor.

• 该合成方法是由邻苯二甲酰亚胺、碳酸钾和2-氯-5-氯甲基吡啶发生Gabriel一步法缩合反应,其缩合产物先在强碱性溶液中水解,水解产物经过水蒸汽蒸馏,重结晶得2-氯-5-氨甲基吡啶。