These results suggest that CAM inhibits the expression of MMP 9 in LCC which may be attributed to the important molecular mechanism of anti angiogenesis of CAM.

• CAM对人小细胞肺癌细胞MMP 9的蛋白表达有明显的抑制作用 ,对VEGF的表达也有一定的抑制作用 ,这种抑制作用可能是CAM抗肿瘤血管生成的分子基础