These results demonstrate the role of CD4+CD25high Tr cells in tumor-induced immune tolerance and the interest of Tr cell depletion to sensitize colorectal cancers to immunotherapy.

 
  • 结论结直肠癌患者外周血CD4+CD25highTr细胞比率明显升高,可能在结直肠癌的发生发展中起重要作用。
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