There is significant association between CYP11B2(-344T/C)polymorphism and essential hypertension in Han nationality in Beijing. CYP11B2(-344T/C)polymorphism is a predictor of antihypertensive effect of Valsartan.

• 醛固酮合成酶基因CYP11B2(-344T/C)多态性与北京汉族人原发性高血压明显相关,并且可能是缬沙坦降压疗效的有效预测因子。