There is polymorphism at 20 exon LEPR gene in children with obesity, which may affect the lipid metabolism and the fat distribution.

• 单纯型肥胖儿童瘦素受体基因第20外显子存在基因多态性的变化,且这种变化明显影响肥胖儿童的脂质代谢及体脂分布。