There is increasing evidence to indicate that imbalance of MMP and TIMP have something to do with various pathologic mechanisms,especially in tumour invasion and metastasis.

• 研究证实,细胞外基质中基质金属蛋白酶及其组织抑制剂的失衡与多种病理机制有关,尤其与肿瘤的侵袭和转移密切相关。