There is a range of findings, including facial abnormalities, that can occur with holoprosencephaly, many of which can be seen in a fetus by ultrasound, so prenatal diagnosis is possible.

• 其症状表现较多，包括面部异常，与前脑无裂畸形同时出现的症状，可以用超声检测，因此产前诊断是可能的。