There are mainly two methods to synthesize morpholine, cyclodehydration of diethanol amine (DBA) with sulfuric acid and cyclocondensation of diethylene glycol(DEG) with NHs in the presence of catalyst.

• 吗啉的生产方法主要有二乙醇胺(DEA)浓酸脱水环化法和二甘醇(DEG)氨解脱水环化法，DEA法原料价格高，DEG法催化剂性能不稳定、活性低。