Then the strain (M3-20), which has 245. 56mg/kg riboflavin, was got. Compared with parent strain, the riboflavin content of the mutation strain was increased by 150%.

• 对所得的菌株进一步进行抗铵突变株的选育，最终得到富含核黄素的营养酵母突变株(M3-20)，其核黄素含量达到245.；56mg/kg，与出发菌株核黄素含量相比提高了约150%25。