Their bodies lose the ability to sense the signals sent by leptin and insulin that tell the brain to slow down food intake and fat storage.

• 蛋白在身体其他部位也出现，但研究人员能去除下丘脑中蛋白活性：下丘脑整合来自脑和身体的食物、饥饿、能量平衡和身体营养信号。