The water soluble salbutamol sulfate (SBT) and levofloxacin hydrochloride (LOF) and insoluble beclomethasone dipropionate (BDP) were used as the models. The SBT and LOF solution, BDP micro-emulsion and BDP ethanol(?) solution were used in the study.

• 选择了水溶性药物硫酸沙丁胺醇(SBT)和盐酸左氧氟沙星(LOF)、水不溶性药物丙酸倍氯米松(BDP)为模型，采用水直接溶解、微乳技术或乙醇溶解的方法制成了水雾剂，进行了大鼠经鼻、Beagle犬经口的吸入试验，并与市售的气雾剂、粉雾剂进行了比较。