The treatment with 10 mg ADV QD over 156 weeks was safe and effective in patients with HBeAg-positive CHB.

• ADV 10 mg/d治疗HBeAg阳性慢性乙型肝炎,可明显抑制HBV DNA的复制,使ALT复常,促进HBeAg的血清学转换,使用安全且耐受性良好。