The thrombin is helpful to the attachment of cells to PLA, and slow release of BMSC from scaffolds increases the area of regeneration bone.

• 研究结果发现：PLA-BMSC复合物具有明显的异位骨形成能力，新生血管增加明显，新形成骨面积增加，成骨细胞活跃且数目增加。凝血酶的加入使细胞流失减少，有助于新骨形成，新形成骨有骨髓腔形成。