The synthesis of 3-chloro-7-hydroxy-4-methylcoumarin from ethyl acetoacetate and resorcinol and the synthesis of comaphos using coumarin as one of main materials were introduced in this paper. The product content is 95%.

• 介绍了以乙酰乙酸乙酯和间苯二酚为原料合成 3 -氯 - 7-羟基 - 4-甲基香豆素 ,再以香豆素为主要原料合成蝇毒磷的工艺 ,产品含量达 95%25。