The suppressive effect of TWP on EAN was associated with the restrain of procedures from gene to mRNA in B7 1 and B7 2, and from mRNA to protein in CD28.

• 雷公藤多甙能减轻ENA的病变程度 ,可能与抑制了B7 1及B7 2的基因转录或转录以上环节和抑制了CD2 8翻译或翻译以上环节有关。