The root powder of Stephania tetrandras was diffused with 0.6% H2SO4 solution and the diffusion passed through D72 resin column.

• 粉防己根粉用0.；6%25稀硫酸渗滤；提取液通过D72树脂柱；然后用氨水乙醇溶液洗脱；丙酮、甲苯结晶纯化得到粉防己碱纯品。