The review summarized the style and structure of TIMPs and its expression and function in myocardial reconstruction and heart failure and myocardiac ischemia reperfusion injury.

• 现就基质金属蛋白酶抑制剂的分类和结构及在心肌重构、心力衰竭、心肌缺血再灌注损伤等的表达及作用作一综述。