The results showed that PLP, activated form of Vitamin B??6?, can efficiently inhibit the effect of TOPO I on relaxed negative superheliex, and the inhibitory effect has positive relativity with PLP quantity.

• 结果表明维生素B6的活性形式PLP能有效地抑制TOPOI松弛负超螺旋的作用,且抑制效应与PLP剂量呈正相关。