The results show that Th1/Th2 imbalance exists in peripheral blood of patients with type 2 diabetic nephropathy,Th cells may play an important role in the occurrence and development of DN.

• 2型糖尿病患者存在Th1/Th2淋巴细胞的失衡,在其肾脏病变发病的不同阶段,存在不同的Th1和Th2优劣势,细胞和体液免疫在肾病发生的不同阶段发挥了不同的作用。