The results indicated that the nonlethal precondition of the mouse model is suitabl; The mice that treated with CD8-DLI showed more severe GVHD than that with whole spleen cell DLI.

• 建立非清髓小鼠异基因骨髓干细胞移植模型条件适宜,且去除CD8+细胞的DLI移植后GVHD比未去除组要严重,移植效果相对较差。