The results demonstrated that there was competitive inhibition between peptides (E7_7-15, E7_66-74, E7_82-90) and epitopes (E7_11-19, E7_49-57), and specific CTLs induction was influenced by the peptides distinctively.

 
  • 第二位氨基酸残基都定位于HLA-A2.;1分子肽结合槽的B凹槽附近; 第二位氨基酸残基的Ca和羧基末端氨基酸残基的Ca之间距离分别为P3 (E7_ 49-57)17
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