The recombinant adenoviruses encoding CD/TK gene under the control of VEGFP could be efficiently generated by using the AdEasier-1 system and presented wonderfully in vitro anti-tumor effect.

• 应用AdEasier1系统可以成功制备含VEGFP驱动CD/TK自杀基因的重组腺病毒,该重组体具有明显的肿瘤杀伤作用。