The real and unrelated sequences (RUS) ere extracted from SCOP database with three criterion, i.e. sequence percent identity less than 10%, E-value greater than 10 and representatives of different folds.

• 本研究中的真实不相关序列取自SCOP数据库,利用三种标准得到了各自的序列文件,即序列相似度小于10%25的序列,E-value大于10的序列,以及取自不同折叠的代表序列。