The purpose of present study was to investigate and confirm whether RSM has direct neuroprotective effect in anoxic cultured natal hippocampal neuronal cells by using morphological changes and heat shock protein 70kDa(HSP70) expression as indicators.

• 本文采用新生大鼠海马神经元培养技术，以细胞形态学及HSP70免疫性细胞表达为指标，首次观察了缺氧条件下培养的海马神经无形态结构及HSP70表达变化及丹参的影响。